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Below is an essay on "Virology" from Anti Essays, your source for research papers, essays, and term paper examples.

Virology I
• Basic terminology
o Virion  a complete virus particle. An infectious particle.
o Capsid  a protein coat which encloses the genome of the virus.
o Nucleocapsid  this is a protein coat which comes into direct contact with the genome.
o Envelope  lipid bilayer which also acts to carry viral glycoproteins.
• There are three main types of structures that viral capsids may take upon:
o Helical
o Icosahedral
o Irregular/pleimorphic
• Capsid/nucleocapsids play multiple roles, however their primary function is to protect the genome from environmental harm.
o Protection from dessication (enveloped viruses are more prone to dessication)
o Protection from gastric acids
o Many capsids will also determine the host range due to the receptors that are present on the surface.
 This may also be used to determine the serology of a virus particle.
o Nucleocapsids often function to make sure the genome is “delivered” to the proper destination.
• The envelope is very similar to the cells lipid bilayer.
o It contains glycoproteins which are largely used for recognition of cell receptor and the ability to gain entry into a cell.
• Viral receptors are those proteins which are part of the envelope or the capsid and will determine the host range of the virus.
• Often times the virion will have a nonstructural component already packaged with it.
o This is largely because the item it needs from the cell is either not readily available or unable to be utilized.
 These consist of viral enzymes: polymerases, reverse transcriptase.
 Others: transcription factors, host defense attack.
• Those proteins which actively contribute to the structure of a complete virion are considered to be structural proteins.
• Those proteins which are not an active part of a complete virion particle and carry out a different function not related to structure are known as non-structural (ie polymerases, TF).
• Taxonomic classification of virus particles are based upon:

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"Virology". Anti Essays. 18 Dec. 2018


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Virology. Anti Essays. Retrieved December 18, 2018, from the World Wide Web: http://parimatch-stavka7.com/free-essays/Virology-311026.html

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